In 2011, Ludovic D'Ambrosio took part in a docu-reality produced by Olivier Hallé (Dans la peau d'un handicapé), La Grande Traversée, with the famous yachtsman Marc Pajot. After sailing around the Mediterranean, he travelled the world for nearly 8 years, living between Ireland and Mexico, where he appeared in a number of local productions.Back in France, Ludovic took acting classes at La Fabrique de l'Acteur (Paris/Marseille), based on the Meisner and Stanislavski methods, with Xavier Laurent (Aix-en-Provence). In 2020, he made his French TV debut in the series Plus Belle La Vie, as a prison guard. Shortly afterwards, he joined the cast of La Chambre des Merveilles, a feature film directed by Lisa Azuelos (LOL, Dalida) in the role of a customs officer at Porto airport (role in English, credited) and returned to the series Plus Belle La Vie to play, this time, the role of a Policeman. He went on to play minor roles in the TV film Champion (directed by Mona Achache, Little Blue Girl) and in the series Mère Indigne.
In 2023, he decided to make a feature film, L'auberge Paradis, in which he also starred. In 2025, the feature film was made available on Prime Video.
He is fluent in English, Spanish and Italian.